Beilstein J. Nanotechnol.2014,5, 778–788, doi:10.3762/bjnano.5.90
characteristics of the glutamatergic neurotransmission were analysed. Using radiolabeled L-[14C]glutamate, it was shown that D-mannose-coated γ-Fe2O3 nanoparticles did not affect high-affinity Na+-dependent uptake, tonic release and the extracellular level of L-[14C]glutamate in isolated ratbrainnerveterminals
uptake and release; manipulation by an external magnetic field; D-mannose; membrane potential; nanoparticles; ratbrainnerveterminals; synaptic vesicle acidification; Introduction
Nanoparticles have great biotechnological potential opening a wide range of new applications. Properties of nanomaterials
uptake of glutamate by ratbrainnerveterminals via specific high-affinity Na+-dependent plasma membrane transporters by using radiolabeled L-[14C]glutamate; (2) the membrane potential (Em) of the plasma membrane of nerve terminals by using potential sensitive fluorescent dye rhodamine 6G; and (3) the
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Figure 1:
Transmission electron micrographs of (a) neat and (b) D-mannose-coated γ-Fe2O3 nanoparticles.